5,5’-Indigodisulfonic acid as an efficient catalyst for the synthesis of 2,3-dihydroquinazolinone derivatives

An efficient protocol for the synthesis of 2,3-dihydroquinazolinone derivatives from substituted 2-aminobenzamides and carbonyl analog catalyzed by natural-based 5,5’-indigodisulfonic acid has been developed with good to excellent yields. Compared reaction conditions reported before, use eco-friendly recyclable catalysts mild are major advantages present method.